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Section: Partnerships and Cooperations
International Initiatives
Participation in International Programs
CAPES/COFECUB project “Modelling innovative control methods for dengue fever" (Bliman)
STIC AmSud project “MOSTICAW- MOdelling the Spread and (opTImal) Control of Arboviroses by Wolbachia" (2016-2017) (Bliman)..
ECOS-Nord project “New methods for controlling epidemics of dengue fever and arboviroses" (2017-2019) (Bliman)
(See below)
International Initiatives
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Title: MOdelling the Spread and (opTImal) Control of Arboviroses by Wolbachia
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International Partners (Institution - Laboratory - Researcher):
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The spread of certain strains of the intracellular parasitic bacterium Wolbachia in populations of mosquitoes Aedes aegypti drastically reduces their competence as vector of dengue and other severe mosquito-borne viral diseases known as arboviral infections. In absence of vaccine, or of preventive or curative treatment, the release of mosquitoes infected by the bacterium has been recently considered a promising tool to control these diseases, and experimental introductions in wild populations are currently under way in Brazil and Colombia. A key question about this method concerns the effective strategies of release of the infected mosquitoes in the field that can be applied with limited cost to reach the desired state of complete exclusion of Wolbachia-free mosquitoes. The mathematical study of central topics is the core of this project. The scientific questions to be addressed during this project are related to the study of the dynamic and control of the key invasion mechanism on finite-dimensional compartmental models; and to specific focus on the spatial aspects, achieved through more elaborate models (PDE, models on interaction graphs, stochastic models). We further propose to elaborate on the risks involved in the spreading of Wolbachia, implementing in mathematical models critical analysis, complex systems (R. García) and a complexity aware epistemology (E. Morin) in contrast with the instrumental reason (Horkheimer).